A randomized clinical trial to compare levonorgestrel-releasing intrauterine system (Mirena) vs tran

Shirin Ghazizadeh,1 Fatemeh Bakhtiari,1 Haleh Rahmanpour,2 Fatemeh Davari-Tanha,1 and Fatemeh Ramezanzadeh1


Abstract

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Objective:

To compare the acceptability, efficacy, adverse effects, and user satisfaction of the levonorgestrel intrauterine system (LNG-IUS) and trans-cervical resection of the endometrium (TCRE) for the treatment of menorrhagia.

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Method:

104 women with menorrhagia were divided into 2 groups: 52 women had the LNG-IUS inserted and 52 underwent TCRE. Menstrual pattern, pictorial blood loss assessment chart score, adverse effects, and rates of acceptability and satisfaction, were recorded at 6 and 12 months after the procedure.

Results:

After a year there were reductions of 93.9% and 88.4% in menstrual blood loss in the TCRE and LNG-IUS groups, respectively. Amenorrhea was more common in the TCRE group and spotting and systemic effects in the LNG-IUS group. Satisfaction rates of the TCRE group were higher than the LNG-IUS group (80.8% vs 69.2%), but the difference was not statistically significant.

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Conclusion:

Although both treatments were found to be equally effective, LNG-IUS was less invasive and can be advised for younger women with a desire to preserve fertility.

Keywords: menorrhagia, trans-cervical endometrial resection, levonorgestrel-releasing intrauterine system

 

Int J Womens Health. 2011; 3: 207–211.

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